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February 1, 2003Obesity Research

Epicardial Fat from Echocardiography: A New Method for Visceral Adipose Tissue Prediction

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Key result

Epicardial adipose tissue thickness measured by echocardiography showed an excellent correlation with MRI abdominal visceral adipose tissue (r = 0.864, p = 0.01).

Why the study?

Does transthoracic echocardiography accurately predict visceral adipose tissue compared to MRI in healthy subjects?

Population

60 healthy subjects (29 women, 31 men), mean age 49.5 +/- 16.2 years, with a wide range of body mass indexes.

Comparison

Transthoracic echocardiography to measure… vs Magnetic resonance imaging to measure epicardial…

Design

Cross-sectional

Authors

GIGianluca IacobellisPreventive CardiologyFAFilippo AssaelOspedale generale di zona San Camillo TrevisoMRMária Cristina RibaudoPoliclinico Umberto I

Discussion

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Implication

Echocardiography may estimate visceral adiposity; leaves open validation for cardiovascular risk stratification in prospective cohorts.

Key Points

  • To evaluate transthoracic echocardiography as an accessible and reliable imaging method for predicting visceral adipose tissue.
  • Assessed 60 healthy subjects (29 women, 31 men, mean age 49.5 ± 16.2 years) across a wide range of body mass indexes.
  • Measured right ventricular epicardial adipose tissue thickness using both transthoracic echocardiography and magnetic resonance imaging (MRI).
  • Quantified abdominal visceral adipose tissue (VAT) cross-sectional areas at L4–L5 via MRI alongside standard anthropometric indexes.
  • Epicardial fat thickness was significantly higher in subjects with visceral versus peripheral fat distribution in men (9.97 ± 2.88 vs. 4.34 ± 1.98 mm, p = 0.005) and women (7.19 ± 2.74 vs. 3.43 ± 1.64 mm, p = 0.004).
  • Epicardial adipose tissue thickness showed strong linear correlations with waist circumference (r = 0.895, p = 0.01) and MRI abdominal VAT (r = 0.864, p = 0.01).
  • Multiple regression analysis identified epicardial adipose tissue thickness as the strongest independent predictor of MRI VAT (r² = 0.442, p = 0.02).

Study Design

Type

Cross-Sectional (n=60)

Structured PICO

Does transthoracic echocardiography accurately predict visceral adipose tissue compared to MRI in healthy subjects?

P
Population
60 healthy subjects (29 women, 31 men), mean age 49.5 +/- 16.2 years, with a wide range of body mass indexes.
I
Intervention
Transthoracic echocardiography to measure epicardial fat thickness on the right ventricle
C
Comparator
Magnetic resonance imaging (MRI) to measure epicardial fat thickness and visceral adipose tissue (VAT) cross-sectional areas
O
Outcome
Correlation between epicardial adipose tissue thickness and MRI abdominal VATsurrogate

Main Result

Effect estimate: r = 0.864

p-value: p=0.01

Transthoracic echocardiography measurement of epicardial fat thickness is a reliable and easy method for predicting visceral adipose tissue, an indicator of cardiovascular risk.

Cite This Study

Iacobellis et al. (2003) conducted a cross-sectional in Healthy subjects (n=60). Transthoracic echocardiography vs. Magnetic resonance imaging (MRI) was evaluated on Correlation between epicardial adipose tissue thickness and MRI abdominal VAT (r = 0.864, p=0.01). Epicardial adipose tissue thickness measured by echocardiography showed an excellent correlation with MRI abdominal visceral adipose tissue (r = 0.864, p = 0.01).

synapsesocial.com/papers/6a14e3e1253bd9cd3ce627dehttps://doi.org/10.1038/oby.2003.45

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.1978 · 7,475 citations
  2. 2Quantitation and Localization of Regional Body Fat Distribution ‐ A Comparison Between Magnetic Resonance Imaging and Somatometry1996 · 14 citations
  3. 3Pseudopericardial effusion: Echocardiographic and computed tomographic correlations1986 · 19 citations
  4. 4Fat Distribution and Health in Obesity2000 · 77 citations
  5. 5Adiposity, Fat Distribution, and Cardiovascular Risk1989 · 426 citations