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April 1, 2001Preventive CardiologyOpen Access

Aerobic Exercise and Resting Blood Pressure: A Meta‐Analytic Review of Randomized, Controlled Trials

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Key result

Aerobic exercise significantly reduced resting systolic and diastolic blood pressure in hypertensive adults by -6 mm Hg (95% CI -8 to -3) and -5 mm Hg (95% CI -7 to -3), respectively.

Why the study?

Does aerobic exercise reduce resting systolic and diastolic blood pressure in adults?

Population

47 clinical trials pooling 2,543 adults, including both hypertensive and normotensive groups.

Comparison

Aerobic exercise vs Control

Design

Meta-analysis

Authors

GKGeorge A. KelleyPreventive CardiologyKKKristi A. KelleyMGH Institute of Health ProfessionsZTZung Vu TranBroomfield Hospital

Discussion

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Implication

Supports aerobic exercise as first-line lifestyle therapy in hypertension; reinforces consensus from Level 1 evidence.

Study Design

Type

Meta-Analysis (n=2,543)

Structured PICO

Does aerobic exercise reduce resting systolic and diastolic blood pressure in adults?

P
Population
47 clinical trials pooling 2,543 adults (1653 exercise, 890 control), including both hypertensive and normotensive groups.
I
Intervention
Aerobic exercise
C
Comparator
Control
O
Outcome
Changes in resting systolic and diastolic blood pressuresurrogate

Main Result

Effect estimate: Mean difference -6 mm Hg (systolic) and -5 mm Hg (diastolic) in hypertensives (95% CI -8 to -3 (systolic), -7 to -3 (diastolic))

p-value: p=0.008 (systolic), 0.000 (diastolic)

Aerobic exercise effectively lowers resting systolic and diastolic blood pressure in both hypertensive and normotensive adults.

Cite This Study

Kelley et al. (2001) conducted a meta-analysis in Hypertension and normotension (n=2,543). Aerobic exercise vs. Control was evaluated on Changes in resting systolic and diastolic blood pressure (Mean difference -6 mm Hg (systolic) and -5 mm Hg (diastolic) in hypertensives, 95% CI -8 to -3 (systolic), -7 to -3 (diastolic), p=0.008 (systolic), 0.000 (diastolic)). Aerobic exercise significantly reduced resting systolic and diastolic blood pressure in hypertensive adults by -6 mm Hg (95% CI -8 to -3) and -5 mm Hg (95% CI -7 to -3), respectively.

synapsesocial.com/papers/6a14e3e1253bd9cd3ce627dfhttps://doi.org/10.1111/j.1520-037x.2001.00529.x

Topics

Hypertension management
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Differential effects of exercise training intensity on blood pressure and cardiovascular responses to stress in borderline hypertensive humans1996 · 97 citations
  2. 2Exercise Training of Men At Retirement: a Clinical Trial1987 · 110 citations
  3. 3Group- vs Home-Based Exercise Training in Healthy Older Men and Women1991 · 408 citations
  4. 4Women walking for health and fitness. How much is enough?1991 · 284 citations