Key result
A nondipping blood pressure pattern (<10% nocturnal reduction) independently predicted frequent or complex ventricular arrhythmias in never-treated hypertensive patients (OR 2.9; 95% CI 1.2-7.0).
Why the study?
Does a nondipping blood pressure pattern increase the frequency and complexity of ventricular arrhythmias in never-treated subjects with essential hypertension?
Cross-Sectional (n=126)
Does a nondipping blood pressure pattern increase the frequency and complexity of ventricular arrhythmias in never-treated subjects with essential hypertension?
Effect estimate: OR 2.9 (95% CI 1.2-7.0)
A nondipping blood pressure pattern is an independent predictor of frequent and complex ventricular arrhythmias in never-treated patients with essential hypertension.
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May inform ambulatory BP monitoring for arrhythmia risk stratification in hypertension; hypothesis-generating for causality and intervention trials.
Schillaci et al. (1996) conducted a cross-sectional in Essential hypertension (n=126). Nondipping blood pressure pattern (<10% nocturnal reduction) vs. Dipping blood pressure pattern was evaluated on Frequent or complex ventricular arrhythmias (Lown class ≥ 2) (OR 2.9, 95% CI 1.2-7.0). A nondipping blood pressure pattern (<10% nocturnal reduction) independently predicted frequent or complex ventricular arrhythmias in never-treated hypertensive patients (OR 2.9; 95% CI 1.2-7.0).
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