February 1, 1995Journal of Hypertension
Ventricular arrhythmias in hypertension
Why the study?
Does long-term antihypertensive therapy increase the prevalence of complex ventricular arrhythmias in hypertensive patients with left ventricular hypertrophy?
Population
120 subjects including 103 untreated subjects and 17 hypertensive patients with LVH on long-term…
Comparison
Long-term antihypertensive therapy vs Untreated hypertensive patients with left…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Associated higher arrhythmia prevalence in treated LVH patients should not alter practice; leaves open confounding versus causal therapy effects.
Structured PICO
Does long-term antihypertensive therapy increase the prevalence of complex ventricular arrhythmias in hypertensive patients with left ventricular hypertrophy?
P
Population
120 subjects including 103 untreated subjects (38 hypertensive with left ventricular hypertrophy [LVH], 16 hypertensive without LVH, 26 borderline or white-coat hypertension, 23 normotensive) and 17 hypertensive patients with LVH on long-term antihypertensive therapy.
I
Intervention
Long-term antihypertensive therapy
C
Comparator
Untreated hypertensive patients with left ventricular hypertrophy (matched for age, sex, and race)
O
Outcome
Prevalence of frequent or complex ventricular arrhythmias (Lown score 2+)surrogate
Long-term antihypertensive therapy in patients with left ventricular hypertrophy is associated with a higher prevalence of complex ventricular arrhythmias compared to untreated patients.
Cite This Study
Mayet et al. (1995) studied this question.