Key result
A combination of Holter variables (HRV, VT, and ST) identified high-risk post-MI patients with a 39% cardiac death rate over 10-12 years compared to 9% in Holter-negative patients (p < 0.0001).
Why the study?
Does a combination of Holter variables (HRV, VT, ST) improve risk stratification for cardiac death in male survivors of a first myocardial infarction?
Population
121 men < 70 years old who are survivors of a first myocardial infarction.
Comparison
24-hour Holter monitoring assessing a… vs Holter negative patients or individual Holter…
Design
Cohort
Follow-up
10-12 years
Authors
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May support combined Holter monitoring for post-MI risk stratification; extends single-variable data but remains hypothesis-generating.
Cohort (n=121)
Does a combination of Holter variables (HRV, VT, ST) improve risk stratification for cardiac death in male survivors of a first myocardial infarction?
Absolute Event Rate: 39% vs 9%
p-value: p=< 0.0001
Combining multiple Holter monitoring variables (HRV, VT, and ST-segment elevation) significantly improves long-term risk stratification for cardiac death in men following a first myocardial infarction.
Vittrup et al. (2002) conducted a cohort in first myocardial infarction (n=121). Combination of Holter variables (HRV, VT, ST) vs. Holter negative patients was evaluated on cardiac death (p=< 0.0001). A combination of Holter variables (HRV, VT, and ST) identified high-risk post-MI patients with a 39% cardiac death rate over 10-12 years compared to 9% in Holter-negative patients (p < 0.0001).
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