Key result
Reduced post-ectopic turbulence slope on Holter monitoring strongly predicted sudden cardiac death among post-AMI patients with preserved left ventricular function (HR 5.9; 95% CI 2.9-11.7, P<0.001).
Why the study?
Does Holter monitoring predict sudden cardiac death in survivors of acute myocardial infarction treated with modern therapy?
Population
2130 survivors of acute myocardial infarction, mean age 59 +/- 10 years, treated with modern therapeutic…
Design
Cohort
Follow-up
median 1012 days (interquartile range: 750-1416 days)
Authors
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Holter monitoring variables, particularly turbulence slope, remain significant predictors of sudden cardiac death in post-AMI patients with preserved ejection fraction receiving modern therapy.
Cohort (n=2,130)
Does Holter monitoring predict sudden cardiac death in survivors of acute myocardial infarction treated with modern therapy?
Hazard Ratio: 5.9 (95% CI 2.9–11.7)
p-value: p=<0.001
Holter monitoring variables, particularly turbulence slope, remain significant predictors of sudden cardiac death in post-AMI patients with preserved ejection fraction receiving modern therapy.
Mäkikallio et al. (2005) conducted a cohort in Acute myocardial infarction (n=2,130). Holter-based risk variables (reduced post-ectopic turbulence slope and non-sustained ventricular tachycardia) vs. Absence of Holter-based risk variables was evaluated on Sudden cardiac death (SCD) (HR 5.9, 95% CI 2.9-11.7, p=<0.001). Reduced post-ectopic turbulence slope on Holter monitoring strongly predicted sudden cardiac death among post-AMI patients with preserved left ventricular function (HR 5.9; 95% CI 2.9-11.7, P<0.001).
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