Key result
Atrial fibrillation and heart failure have a mutually deleterious effect on each other, with AF acting as both a marker of HF severity and an independent predictor of adverse HF prognosis.
Atrial fibrillation and heart failure frequently coexist and have a bidirectional, mutually deleterious pathophysiological and prognostic relationship.
Supports integrated AF-HF screening; leaves open optimal rhythm-control strategies in HF.
Heart failure (HF) and atrial fibrillation (AF) are among the commonest cardiovascular conditions encountered in clinical practice and frequently coexist. Over the last decade, they have evolved into global cardiovascular epidemics. This, in turn, has huge clinical and economic implications. There is ample evidence that AF and HF have a mutually deleterious effect on each other. AF is not only a marker of HF severity but also affects HF prognosis independently. This article presents the close pathophysiological relationship between AF and HF and the adverse prognostic consequences of this bidirectional interaction. The scope of various therapeutic modalities and their potential impacts are discussed briefly.
No takes yet. Share an insight, caveat, or question.
Khan et al. (2016) conducted a review in Heart failure and atrial fibrillation. Atrial fibrillation and heart failure have a mutually deleterious effect on each other, with AF acting as both a marker of HF severity and an independent predictor of adverse HF prognosis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: