Key result
An autoantibody screening test using sera from dogs with spontaneous dilated cardiomyopathy identified 5 potentially DCM-related autoantigens, including 3 novel targets.
Identified three novel autoantigens in a canine model of spontaneous DCM, providing new insights into autoimmune mechanisms of the disease.
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Provides candidate autoantigens for DCM research; hypothesis-generating in dogs and should not yet influence human practice.
Buse et al. (2008) studied Dilated cardiomyopathy. Autoantibody screening test was evaluated on Identification of DCM-related autoantigens. An autoantibody screening test using sera from dogs with spontaneous dilated cardiomyopathy identified 5 potentially DCM-related autoantigens, including 3 novel targets.
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