Key result
Subcutaneous ECG leads provided 98.9% positive predictive value and 98.9% sensitivity for counterpulsation device triggering compared to epicardial leads in a calf model.
Why the study?
Do subcutaneous ECG leads provide accurate R-wave detection for triggering counterpulsation devices compared to epicardial leads in chronic ischemic heart failure calves?
Population
Chronic ischemic heart failure calves implanted with counterpulsation devices (CPDs)
Comparison
Subcutaneous ECG leads vs Clinical-grade epicardial ECG leads (control)
Design
Preclinical
Follow-up
up to 30 days
Authors
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May support less invasive triggering in preclinical counterpulsation; leaves open human translation.
Do subcutaneous ECG leads provide accurate R-wave detection for triggering counterpulsation devices compared to epicardial leads in chronic ischemic heart failure calves?
Subcutaneous ECG leads provide highly sensitive and specific R-wave detection for counterpulsation device timing in a preclinical model, offering a potentially less invasive alternative to epicardial leads.
Carnahan et al. (2016) studied Chronic ischemic heart failure. Subcutaneous ECG leads vs. Epicardial ECG leads was evaluated on Sensitivity and specificity of CPD triggering by R-wave detection. Subcutaneous ECG leads provided 98.9% positive predictive value and 98.9% sensitivity for counterpulsation device triggering compared to epicardial leads in a calf model.
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