Key result
Conventional echocardiographic parameters strongly correlated with CMR-derived right ventricular ejection fraction, identifying a 47.3% prevalence of right ventricular dysfunction in HNDC patients.
Why the study?
Right ventricular function is an important prognostic factor in heart failure, but required evaluation in patients with hypokinetic non-dilated cardiomyopathy.
Does conventional echocardiographic RV dysfunction score correlate with CMR-derived RVEF in patients with hypokinetic non-dilated cardiomyopathy?
Observational (n=31)
Does conventional echocardiographic RV dysfunction score correlate with CMR-derived RVEF in patients with hypokinetic non-dilated cardiomyopathy?
In patients with hypokinetic non-dilated cardiomyopathy, RV dysfunction is highly prevalent (47.3%) and can be appropriately assessed using conventional echocardiographic parameters which correlate strongly with CMR-derived RVEF.
Answers are grounded in this paper and cite their sources.
May support conventional echo for RV assessment in HNDC; leaves open outcome validation before practice change.
Background: Hypokinetic non-dilated cardiomyopathy (HNDC) is a subgroup of dilated cardiomyopathy (DCM) spectrum, known by left ventricular (LV) systolic dysfunction despite normal LV size. Objectives: In this study, we are going to evaluate right ventricular (RV) function in these patients as an important prognostic factor in HF patients. Methods: 31 HNDC patients were enrolled in the study. RV function was evaluated by TTE using RV dysfunction score calculated as the summation of TAPSE, RV Sâ, RVMPI, and RVFAC scores. Ultimately, echocardiographic data were compared to right ventricular ejection fraction (RVEF) obtained from cardiac magnetic resonance imaging (CMR). Results: The prevalence of RV at dysfunction was estimated at 47.3%. Furthermore, we found a strong negative correlation between RV dysfunction score and CMR-RVEF. Conclusions: RV Sâ, RVFAC, and RVMPI would offer an appropriate assessment of RV function in HNDC group. HNDC population exhibited RV dysfunction as prevalent as DCM patients reported in other studies.
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Parsaee et al. (2019) conducted an observational in Hypokinetic non-dilated cardiomyopathy (HNDC) (n=31). Conventional echocardiography (RV dysfunction score) vs. Cardiac magnetic resonance imaging (CMR) was evaluated on Prevalence of right ventricular dysfunction and correlation between RV dysfunction score and CMR-RVEF. Conventional echocardiographic parameters strongly correlated with CMR-derived right ventricular ejection fraction, identifying a 47.3% prevalence of right ventricular dysfunction in HNDC patients.
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