Key result
RV systolic dysfunction affects ~65% of patients with dilated cardiomyopathy, linked to reduced RV strain.
Why the study?
Right ventricular function plays a crucial role in prognosis of dilated cardiomyopathy but is less frequently assessed than left ventricular function, necessitating characterization of RV alterations using advanced echocardiographic techniques.
Cross-Sectional (n=40)
No
Right ventricular systolic dysfunction is highly prevalent in dilated cardiomyopathy and can be effectively detected and stratified using speckle-tracking echocardiography.
Answers are grounded in this paper and cite their sources.
RVSD assessment may refine DCM evaluation; leaves open whether strain-guided interventions alter prognosis.
Objectives Dilated cardiomyopathy (DCM) is a disorder with myocardial involvement invariably associated with left ventricular (LV) systolic dysfunction and progressive disorder chamber enlargement. Although LV assessment predominates in clinical evaluation, right ventricular (RV) function plays a crucial role in determining prognosis. This study of DCM uses advanced echocardiographic techniques. To characterize alterations in RV size and function in DCM and determine the prevalence of RV systolic dysfunction (RVSD) based on echocardiographic parameters. Material and Methods In this cross-sectional observational study, 40 patients with DCM (mean age: 53.3 ± 15.7 years; 72.5% male) underwent comprehensive 2D and speckle-tracking echocardiography. Parameters assessed included right atrial (RA) area, tricuspid annular plane systolic excursion (TAPSE), RV strain, fractional area change (FAC), myocardial performance index (MPI), RVS′, and RV length. Demographic, clinical, and electrocardiographic data were noted. RVSD was defined according to guideline-based echocardiographic cutoffs. Results RVSD was present in 26 of 40 patients (65%; 95% CI: 48.3–79.4%), while 14 patients (35%) had preserved RV function. Patients with RVSD exhibited significantly larger RA dimensions and reduced TAPSE, RV strain, FAC, and increased MPI (all p < 0.001). RVS′ ( p = 0.003) and RV length ( p = 0.02) also differed significantly between groups. Conclusion DCM has RV dysfunction in addition to LV dysfunction and is highly prevalent, and is associated with significant alterations in multiple echocardiographic indices. Given its prognostic importance, routine assessment of RV function, particularly by speckle-tracking echocardiography, should be integrated into the standard evaluation of patients with DCM.
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Seshachar et al. (2026) conducted a cross-sectional in Dilated cardiomyopathy (n=40). Dilated cardiomyopathy was evaluated on Prevalence of right ventricular systolic dysfunction (95% CI 48.3-79.4). Right ventricular systolic dysfunction was highly prevalent, occurring in 65% of patients with dilated cardiomyopathy, and was associated with significantly reduced right ventricular strain.
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