Key result
Current smoking in adults aged ≥60 years increased the risk of cardiovascular mortality compared with never smoking (HR 2.07; 95% CI 1.82-2.36), advancing cardiovascular mortality by 5.50 years.
Why the study?
Does smoking and smoking cessation impact cardiovascular events and mortality in adults aged 60 and older?
Population
503,905 adults aged 60 and older from 25 prospective cohorts participating in the CHANCES consortium
Comparison
Current smoking and former smoking vs Never smoking
Design
Meta-analysis
Authors
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Strengthens smoking cessation counseling for adults ≥60 years; confirms persistent cardiovascular mortality risk elevation.
Meta-Analysis (n=503,905)
Yes
Does smoking and smoking cessation impact cardiovascular events and mortality in adults aged 60 and older?
Effect estimate: HR 2.07 (95% CI 1.82 to 2.36)
Smoking remains a strong independent risk factor for cardiovascular mortality in adults aged 60 and older, advancing mortality by over 5 years, though smoking cessation significantly reduces this excess risk.
Mons et al. (2015) conducted a meta-analysis in Cardiovascular events and mortality (n=503,905). Current smoking vs. Never smokers was evaluated on Cardiovascular mortality (HR 2.07, 95% CI 1.82 to 2.36). Current smoking in adults aged ≥60 years increased the risk of cardiovascular mortality compared with never smoking (HR 2.07; 95% CI 1.82-2.36), advancing cardiovascular mortality by 5.50 years.
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