Key result
Computational model successfully simulates athlete blood gas and lactate transport during prolonged moderate exercise.
A novel computational model can simulate metabolic parameters during treadmill testing to evaluate physical endurance in athletes.
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May support simulated endurance assessment in athletes; leaves open clinical validation before practice use.
In this work, we propose a model of the transport and balance of blood gases and lactate in the blood. The model includes regulation of the respiratory minute volume and cardiac output basing on the partial pressures of oxygen and carbon dioxide in the central and peripheral regulators. The model consists of lumped compartments, which represent the lungs and parts of the circulatory system. For each blood compartment, we solve the equations of haemoglobin oxygenation, acid-base balance, aerobic and anaerobic energy production and consumption, lactate production and utilisation. The treadmill test with increasing load gives input parameters to the model. The model allows simulations of metabolic parameters of athletes during prolonged moderate physical exercise and evaluates their physical endurance.
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Golov et al. (2020) studied Physical endurance. Computational model of blood gases and lactate transport was evaluated on Simulation of metabolic parameters and evaluation of physical endurance. A proposed computational model of blood gas and lactate transport successfully simulates metabolic parameters in athletes during prolonged moderate exercise to evaluate physical endurance.
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