Key result
In 390 male workers, glucose and insulin levels significantly correlated with relative wall thickness independent of blood pressure, suggesting they promote concentric left ventricular changes.
Why the study?
Does hyperglycemia or hyperinsulinemia influence left ventricular mass and geometry in normotensive and mildly to moderately hypertensive men?
Population
390 male workers in a bus company, free from cardiac diseases, not taking medication for hypertension and…
Design
Cross-sectional
Authors
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Should not yet change practice; hypothesis-generating for metabolic effects on LV geometry.
Cross-Sectional (n=390)
Does hyperglycemia or hyperinsulinemia influence left ventricular mass and geometry in normotensive and mildly to moderately hypertensive men?
Hyperglycemia and hyperinsulinemia are independently associated with concentric left ventricular geometric changes in men without known cardiac disease.
Ohya et al. (1996) conducted a cross-sectional in Normotension and mild to moderate hypertension (n=390). Hyperglycemia and hyperinsulinemia (Exposure) was evaluated on Left ventricular mass and geometry (relative wall thickness and left ventricular mass index). In 390 male workers, glucose and insulin levels significantly correlated with relative wall thickness independent of blood pressure, suggesting they promote concentric left ventricular changes.
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