Key result
Pharmacist interventions reduce all-cause mortality ~28% and hospitalizations in HF vs usual care.
Why the study?
Heart failure patients often face complex regimens and adherence issues, but evidence of pharmacists contributions to improving clinical outcomes remains limited.
Do pharmacist interventions reduce all-cause mortality and hospitalizations and improve quality of life in adult heart failure patients compared to usual care?
Comparison
Pharmacist interventions vs usual care
Design
Systematic review and random-effects meta-analysis of RCTs
Authors
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Supports integrating pharmacists into heart failure care teams; reinforces consensus on multidisciplinary management.
Meta-Analysis (n=6,965)
Do pharmacist interventions reduce all-cause mortality and hospitalizations and improve quality of life in adult heart failure patients compared to usual care?
Effect estimate: RR 0.72 (95% CI 0.58-0.89)
p-value: p=0.003
Integration of pharmacist interventions into heart failure care significantly reduces all-cause mortality and hospitalizations while improving patient quality of life.
Arunmanakul et al. (2021) conducted a meta-analysis in Heart failure (n=6,965). Pharmacist interventions vs. Usual care was evaluated on All-cause mortality (RR 0.72, 95% CI 0.58-0.89, p=0.003). Pharmacist interventions in heart failure patients significantly reduced all-cause mortality (RR 0.72; 95% CI 0.58-0.89; P=0.003) and all-cause hospitalizations compared with usual care.
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