Key result
In a litter of five 18-month-old mixed-breed cats diagnosed with hypertrophic cardiomyopathy, all remained free of overt clinical signs two years following diagnosis despite having systolic murmurs.
Case Report (n=5)
This case series documents familial hypertrophic cardiomyopathy in a litter of mixed-breed cats, highlighting an asymptomatic presentation with echocardiographic abnormalities that remained stable over 2 years.
Asymptomatic feline HCM may remain stable over 2 years; leaves open prognostic implications and need for larger studies.
A litter of five, 18-month-old, mixed-breed cats were determined to have hypertrophic cardiomyopathy (HCM). Although no overt clinical signs were present in any cat, systolic heart murmurs were present in each. Electrocardiograms were normal, while subjective interpretations of heart enlargement on radiographs were made on four cats. Echocardiographic analyses indicated abnormalities consistent with HCM. Overt clinical signs are absent two years following diagnosis.
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Kraus et al. (1999) conducted a case report in Hypertrophic cardiomyopathy (HCM) (n=5). In a litter of five 18-month-old mixed-breed cats diagnosed with hypertrophic cardiomyopathy, all remained free of overt clinical signs two years following diagnosis despite having systolic murmurs.
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