November 15, 1995Circulation
Radiofrequency Catheter Modification of Sinus Pacemaker Function Guided by Intracardiac Echocardiography
Key result
Radiofrequency catheter modification of sinus pacemaker function guided by intracardiac echocardiography significantly decreased intrinsic heart rate by 31% (P < .001) in dogs.
Why the study?
Does radiofrequency catheter modification guided by intracardiac echocardiography reduce intrinsic heart rate in a canine model?
Population
15 dogs (11 in group 1 for sinus pacemaker modification, 4 in group 2 for total sinus pacemaker ablation)
Design
Preclinical
Follow-up
3.7 +/- 1.0 months
Authors
Discussion
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Member takes
Implication
Hypothesis-generating for sinus rate control in inappropriate sinus tachycardia; requires human trials before clinical consideration.
Structured PICO
Does radiofrequency catheter modification guided by intracardiac echocardiography reduce intrinsic heart rate in a canine model?
P
Population
15 dogs (11 in group 1 for sinus pacemaker modification, 4 in group 2 for total sinus pacemaker ablation)
I
Intervention
Graded applications of radiofrequency energy along the crista terminalis guided by intracardiac echocardiography
O
Outcome
Reduction in intrinsic heart ratesurrogate
Main Result
p-value: p=<.001
Radiofrequency catheter modification guided by intracardiac echocardiography is feasible for sinus rate control in a canine model, preserving pacemaker stability and autonomic responsiveness.
Cite This Study
Kalman et al. (1995) studied Sinus rate control (animal model) (n=15). Radiofrequency catheter modification of sinus pacemaker function guided by intracardiac echocardiography vs. Total sinus pacemaker ablation or baseline was evaluated on Reduction in intrinsic heart rate (p=<.001). Radiofrequency catheter modification of sinus pacemaker function guided by intracardiac echocardiography significantly decreased intrinsic heart rate by 31% (P < .001) in dogs.