Why the study?
Does epicardial laser photocoagulation of the sinus node reduce maximum heart rates in a canine model?
Population
17 open-chest dogs (14 intervention, 3 control)
Comparison
Epicardial neodymium:YAG laser photocoagulation… vs Sham operation
Design
Preclinical
Follow-up
up to 10 weeks or 6 months
Authors
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May support nonpharmacologic rate control; leaves open translation to human AF management.
Does epicardial laser photocoagulation of the sinus node reduce maximum heart rates in a canine model?
Map-guided graded epicardial laser photocoagulation of the sinus node successfully limits maximum heart rates without causing significant bradycardia in a canine model, suggesting potential as a nonpharmacologic heart rate control strategy.
Littmann et al. (1990) studied this question.
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