Key result
Handheld radiofrequency probes produced deep linear lesions in the myocardium of dogs, with lesion depth increasing from 3.8 mm at 15 s to 6.1 mm at 120 s at 80 degrees C (P=0.01).
Why the study?
Does varying electrode size, temperature, and duration affect the size and shape of radiofrequency lesions in open-chested dogs?
Population
Open-chested dogs
Comparison
Radiofrequency ablation using handheld… vs Different ablation durations, target…
Design
Preclinical
Authors
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May guide surgical RF device parameters; leaves open human safety and efficacy.
Does varying electrode size, temperature, and duration affect the size and shape of radiofrequency lesions in open-chested dogs?
p-value: p=0.01
Handheld radiofrequency probes can create deep, wide linear lesions in the myocardium, with lesion depth increasing significantly with longer ablation duration.
Thomas et al. (2001) studied Atrial fibrillation surgery (animal model). Handheld radiofrequency ablation devices vs. Different electrode sizes, temperatures, and durations was evaluated on Lesion depth and size (p=0.01). Handheld radiofrequency probes produced deep linear lesions in the myocardium of dogs, with lesion depth increasing from 3.8 mm at 15 s to 6.1 mm at 120 s at 80 degrees C (P=0.01).
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