What question did this study set out to answer?

To evaluate the efficacy of very large distal electrodes in producing lesions during radiofrequency catheter ablation compared to conventional electrodes.

July 1, 1993CirculationOpen Access

Temperature-guided radiofrequency catheter ablation with very large distal electrodes.

Q: What is the clinical evidence from this study?

Study design: Other. Population: Radiofrequency catheter ablation (n=10). Intervention: Very large distal electrodes (8F, 8 and 12 mm long) vs. Conventional radiofrequency ablation catheter (distal electrode 8F, 4 mm long). Primary outcome: Lesion depth and volume (p=<.001).

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Key result

Ablation with an 8-mm electrode produced lesions nearly twice as deep (11 vs 6 mm, P<.001) and four times as large (905 vs 210 mm3, P<.001) as those made with a conventional 4-mm electrode.

Authors

JLJonathan J. LangbergElectrophysiology MGM. GallagherSt George's, University of London SSS A StrickbergerUniversity of Maryland, Baltimore

Discussion

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Implication

May support deeper ablation with 8-mm electrodes; leaves open effects on clinical success and safety.

Key Points

To evaluate the efficacy of very large distal electrodes in producing lesions during radiofrequency catheter ablation compared to conventional electrodes.
Conducted in 10 dogs with three catheter types (8F, 4 mm; 8F, 8 mm; 8F, 12 mm).
Ablation performed at 80 degrees C for 60 seconds under fluoroscopic guidance.
Power required and lesion characteristics (depth, volume) measured and compared.
Lesions from the 8-mm electrode were deeper (11 +/- 2.4 mm) and larger (905 +/- 410 mm3) than those from the 4-mm electrode (6 +/- 1.2 mm, 210 +/- 100 mm3, P < .001).
The 12-mm electrode produced intermediate lesions (depth: 8 +/- 1.2 mm; volume: 465 +/- 225 mm3).
Larger electrodes resulted in decreased arterial pressure and increased ventricular ectopy compared to the 4-mm electrode.

PICO

Population

Radiofrequency catheter ablation (n=10)

Intervention / Comparator

Very large distal electrodes (8F, 8 and 12 mm long) vs Conventional radiofrequency ablation catheter (distal electrode 8F, 4 mm long) (80 degrees C for 60 seconds)

Primary Outcome

Lesion depth and volume, p=<.001

Main Result

p-value: p=<.001

Cite This Study

Langberg et al. (1993) studied Radiofrequency catheter ablation (n=10). Very large distal electrodes (8F, 8 and 12 mm long) vs. Conventional radiofrequency ablation catheter (distal electrode 8F, 4 mm long) was evaluated on Lesion depth and volume (p=<.001). Ablation with an 8-mm electrode produced lesions nearly twice as deep (11 vs 6 mm, P<.001) and four times as large (905 vs 210 mm3, P<.001) as those made with a conventional 4-mm electrode.

synapsesocial.com/papers/6a0ff561fb2817e31dfcd824 https://doi.org/10.1161/01.cir.88.1.245

Topics

Ventricular arrhythmias AF ablation outcomes

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Temperature-guided radiofrequency catheter ablation with very large distal electrodes.

Discussion

Member takes

Implication

Key Points

PICO

Main Result

Cite This Study

Topics

Temperature-guided radiofrequency catheter ablation with very large distal electrodes.

Discussion

Member takes

Implication

Key Points

PICO

Main Result

Cite This Study

Also Consider

Topics

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