Population
Anesthetized, open-chest dogs (n=12 total; 7 for papillary muscle sites, 5 for anterior free wall sites)
Comparison
Measurement of three-dimensional regional… vs Anterior free wall sites
Design
Preclinical
Authors
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May affect regional LV assessment in models; extends conflicting prior reports but leaves open human translation.
This preclinical study demonstrates that regional mechanics of the left ventricular wall are depressed near the anterior papillary muscle insertion compared to the free wall, highlighting the structural complexity of this region.
Holmes et al. (1995) studied this question.
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