Why the study?
Does chordal transsection alter regional myocardial deformation near the papillary muscle insertion site in open-chest dogs?
Population
6 open-chest dogs
Comparison
Chordal transsection with placement of a… vs Baseline (prior to chordal transsection)
Design
Preclinical
Authors
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Chordal preservation may avoid regional unloading in mitral surgery; animal findings leave open translation to human ventricular function.
Does chordal transsection alter regional myocardial deformation near the papillary muscle insertion site in open-chest dogs?
Chordal transsection induces regional strain nonuniformity and unloading of the myocardium at the papillary muscle insertion site, explaining the reduced global function and slowed ventricular relaxation observed after mitral valve replacement.
Takayama et al. (1996) studied this question.
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