Population
5 open-chest dogs
Comparison
Acute pressure and volume overload, inotropic… vs Baseline state / comparison between papillary…
Design
Preclinical
Authors
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Papillary ischemia induces severe regional dysfunction; leaves open translation to human mitral regurgitation or ventricular mechanics.
The study demonstrates that anterior left ventricular papillary muscle shortening is substantially less than that of the free wall and exhibits severe dysfunction with systolic elongation during regional ischemia.
Hirakawa et al. (1977) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: