Key result
Total pulmonary vein isolation kept 57% of persistent AF and 84% of paroxysmal AF patients free from symptomatic AF without antiarrhythmic drugs at 11 months (p=0.04).
Why the study?
Does isolation of all four pulmonary veins prevent symptomatic AF recurrence in patients with persistent AF compared to paroxysmal AF?
Population
68 consecutive patients with paroxysmal and persistent atrial fibrillation, mean age 52 ± 10 years.
Comparison
Isolation of all four pulmonary veins by… vs Patients with paroxysmal AF undergoing the same…
Design
Cohort
Follow-up
mean 11 months
Authors
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May support total PVI for symptomatic AF freedom in both types; leaves open randomized trials to improve persistent AF outcomes.
Cohort (n=68)
Does isolation of all four pulmonary veins prevent symptomatic AF recurrence in patients with persistent AF compared to paroxysmal AF?
Absolute Event Rate: 57% vs 84%
p-value: p=0.04
Total pulmonary vein isolation by radiofrequency application is an effective treatment for both paroxysmal and persistent atrial fibrillation.
Matsuo et al. (2005) conducted a cohort in Paroxysmal and persistent atrial fibrillation (n=68). Total pulmonary vein isolation vs. Paroxysmal AF (established efficacy baseline) was evaluated on Freedom from symptomatic AF without any antiarrhythmic drug (AAD) therapy (p=0.04). Total pulmonary vein isolation kept 57% of persistent AF and 84% of paroxysmal AF patients free from symptomatic AF without antiarrhythmic drugs at 11 months (p=0.04).
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