Diabetes and Idiopathic Cardiomyopathy
Key result
Diabetes was independently associated with nonischemic idiopathic cardiomyopathy in the general U.S. population (adjusted OR 1.58; 95% CI 1.55-1.62).
Why the study?
Is diabetes independently associated with nonischemic idiopathic cardiomyopathy in the general population?
Population
495,091 individuals from the 1995 Nationwide Inpatient Sample in the US, including 44,837 cases with…
Comparison
Diabetes (exposure) vs No diabetes
Design
Case-control
Authors
Discussion
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Member takes
Implication
Supports diabetic cardiomyopathy hypothesis; leaves open prospective validation before clinical implications.
Study Design
Type
Case-Control (n=495,091)
Multicenter
Yes
Structured PICO
Is diabetes independently associated with nonischemic idiopathic cardiomyopathy in the general population?
P
Population
495,091 individuals from the 1995 Nationwide Inpatient Sample (NIS) in the US, including 44,837 cases with nonischemic idiopathic cardiomyopathy (ICM) and 450,254 age-stratified control subjects.
I
Intervention
Diabetes (exposure)
C
Comparator
No diabetes
O
Outcome
Diagnosis of nonischemic idiopathic cardiomyopathy (ICM)hard clinical
Main Result
Effect estimate: OR 1.58 (95% CI 1.55-1.62)
Absolute Event Rate: 26.6% vs 17.2%
Diabetes is independently associated with an increased risk of nonischemic idiopathic cardiomyopathy, supporting the existence of diabetic cardiomyopathy.
Cite This Study
Bertoni et al. (2003) conducted a case-control in Idiopathic cardiomyopathy (n=495,091). Diabetes vs. Control subjects was evaluated on Idiopathic cardiomyopathy (OR 1.58, 95% CI 1.55-1.62). Diabetes was independently associated with nonischemic idiopathic cardiomyopathy in the general U.S. population (adjusted OR 1.58; 95% CI 1.55-1.62).