Key result
A tailored approach for heart failure pharmacotherapy during hospitalization and immediately after discharge reduces early adverse events and hospital readmissions.
Why the study?
Early rehospitalisation after an acute heart failure event negatively affects management and survival rates, highlighting the need for tailored pharmacotherapy during and immediately after discharge.
Does the initiation and continuation of guideline-directed medical therapy during and immediately after hospitalization reduce early rehospitalisations in patients with acute decompensated heart failure?
Does the initiation and continuation of guideline-directed medical therapy during and immediately after hospitalization reduce early rehospitalisations in patients with acute decompensated heart failure?
A tailored approach to initiating and maintaining guideline-directed medical therapy during the vulnerable post-discharge phase is essential to reduce early rehospitalizations in acute heart failure.
Supports tailored GDMT in acute HF hospitalization; leaves open prospective RCTs before practice change.
Heart failure (HF) is a pandemic syndrome characterised by raised morbidity and mortality. An acute HF event requiring hospitalisation is associated with a poor prognosis, in both the short and the long term. Moreover, early rehospitalisation after discharge negatively affects HF management and survival rates. Cardiovascular and non-cardiovascular conditions combine to increase rates of HF hospital readmission at 30 days. A tailored approach for HF pharmacotherapy while the patient is in hospital and immediately after discharge could be useful in reducing early adverse events that cause rehospitalisation and, consequently, prevent worsening HF and readmission during the vulnerable phase after discharge.
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Iacovoni et al. (2019) conducted a review in Acute Decompensated Heart Failure. Heart failure pharmacotherapy was evaluated. A tailored approach for heart failure pharmacotherapy during hospitalization and immediately after discharge reduces early adverse events and hospital readmissions.
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