Key result
Intracardiac PES in mice maps atrial and ventricular electrical activity and reveals pacing-induced arrhythmia susceptibility.
Why the study?
Spontaneous arrhythmias are uncommon in healthy young mice, necessitating intracardiac programmed electrical stimulation to assess arrhythmia susceptibility and proarrhythmogenic substrates.
Population
Mouse models for studying cardiac arrhythmias
Design
Protocol description
Authors
Loading...
Enables arrhythmia phenotyping in mouse models; leaves open clinical translation pending human studies.
Provides a detailed protocol for performing in vivo cardiac electrophysiology in mice to assess arrhythmic substrates.
Navarro‐García et al. (2024) studied Cardiac arrhythmias. Intracardiac programmed electrical stimulation (PES) was evaluated. Intracardiac programmed electrical stimulation (PES) in mice provides insights into atrial and ventricular electrical activity and reveals susceptibility to pacing-induced arrhythmias.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: