Why the study?
Do multiple high-energy transthoracic shocks increase acute mortality and cardiac damage compared to a single shock in a healthy animal model?
Population
Healthy greyhounds (n=41)
Comparison
Multiple transthoracic direct current shocks vs Single transthoracic direct current shock (400 J)
Design
Preclinical
Follow-up
3 days
Authors
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Multiple shocks may increase mortality and damage in animals; challenges defibrillation safety assumptions and leaves open human translation.
Do multiple high-energy transthoracic shocks increase acute mortality and cardiac damage compared to a single shock in a healthy animal model?
Multiple high-energy defibrillator shocks cause significant cardiac injury and acute pump failure in a healthy animal model, emphasizing the need for optimized first-shock effectiveness.
Wilson et al. (1988) studied this question.
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