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February 1, 2001Journal of Hypertension263 citations

Electronic compliance monitoring in resistant hypertension: the basis for rational therapeutic decisions

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Why the study?

Does electronic monitoring of drug compliance improve blood pressure control in patients with resistant hypertension?

Population

41 hypertensive patients resistant to a three-drug regimen, with an average baseline blood pressure of…

Design

Cohort

Follow-up

up to 4 months

Key result

Electronic monitoring of drug compliance in patients with resistant hypertension significantly improved blood pressure at 2 months (from 156/106 to 145/97 mmHg, P<0.01).

Authors

MBMichel BurnierMSMarie Paule SchneiderACArnaud Chioléro

Discussion

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Overview

Electronic monitoring was associated with BP improvement in resistant hypertension; hypothesis-generating and requires RCTs before practice change.

Study Design

Type

Observational (n=41)

Structured PICO

Does electronic monitoring of drug compliance improve blood pressure control in patients with resistant hypertension?

P
Population
41 hypertensive patients resistant to a three-drug regimen, with an average baseline blood pressure of 156/106 +/- 23/11 mmHg.
I
Intervention
Electronic monitoring of drug compliance for 2 months (with presently prescribed drugs provided in electronic monitors without treatment change), followed by an optional 2-month extension with treatment adaptation.
O
Outcome
Change in blood pressure at 2 months.surrogate

Electronic monitoring of drug compliance significantly improves blood pressure in patients with resistant hypertension by unmasking non-compliance and guiding therapeutic decisions.

Main Result

p-value: p=< 0.01

Cite This Study

Burnier et al. (2001) conducted an observational in Resistant hypertension (n=41). Electronic monitoring of drug compliance vs. Baseline was evaluated on Blood pressure at 2 months (p=< 0.01). Electronic monitoring of drug compliance in patients with resistant hypertension significantly improved blood pressure at 2 months (from 156/106 to 145/97 mmHg, P<0.01).

synapsesocial.com/papers/6a156e4ea2352da347826d0bhttps://doi.org/10.1097/00004872-200102000-00022
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Blood pressure screening, management and control in England1998 · 316 citations
  2. 2Role of Blood Pressure in the Development of Congestive Heart Failure1972 · 608 citations
  3. 3Compliance with Antihypertensive Therapy1999 · 101 citations
  4. 4Use of electronic pill boxes to assess risk of poor treatment compliance Results of a large-scale trial1999 · 53 citations
  5. 5Resistant Hypertension in a Tertiary Care Clinic1991 · 183 citations