Key result
Among 121 scorpion sting patients, 54.5% developed hypertension, 18.8% had pulmonary edema, and 8.5% died, with outcomes dependent on time to hospitalization and vasodilator administration.
Why the study?
Does early hospitalization and vasodilator therapy reduce cardiovascular morbidity and mortality in patients with scorpion stings?
Observational (n=121)
Yes
Does early hospitalization and vasodilator therapy reduce cardiovascular morbidity and mortality in patients with scorpion stings?
Scorpion envenomation causes significant cardiovascular morbidity and mortality, which can be mitigated by early hospitalization and targeted vasodilator therapy.
May support prompt hospitalization and vasodilators in scorpion stings; hypothesis-generating from Level 5 data, needs prospective trials.
Scorpion sting is a hazardous and potentially lethal condition. One hundred twenty-one scorpion sting patients were admitted to hospitals in Mahad Maharashtra state, India, during 1986–89. Sixty-six (54.5%) victims had hypertension (mean blood pressure 96 to 160 [average 118.6] mmHg). Twenty-four (19.5%) victims demonstrated tachycardia, with heart rates ranging from 110 to 215 (average 156) beats per minute. Twenty-two (18.8%) had pulmonary edema, while nine (8.5%) died. Analysis of our data suggests that cardiovascular morbidity and mortality depends upon the time between the stings and hospitalization or administration of vasodilators. Current management of scorpion envenomation consists of rapid reduction of hypertension with sublingual nifedipine, postsynaptic alpha adrenergic blockade with prazosin hydrochloride, and digoxin therapy for myocardial failure. Massive pulmonary edema can be treated with sodium nitroprusside. In our setting, mortality is reduced by early hospitalization, even though specific antivenin is not available in India.
No takes yet. Share an insight, caveat, or question.
Bawaskar et al. (1991) conducted an observational in Scorpion sting (n=121). Among 121 scorpion sting patients, 54.5% developed hypertension, 18.8% had pulmonary edema, and 8.5% died, with outcomes dependent on time to hospitalization and vasodilator administration.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: