July 1, 1982Annals of Internal Medicine
Alpha-Adrenergic Receptor Blockade with Prazosin
Key result
Prazosin is an effective alpha-1 selective adrenergic antagonist that provides sustained antihypertensive effects and hemodynamic improvement in congestive heart failure.
Population
Patients with hypertension, congestive heart failure, or peripheral vasospasm
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
May inform historical use of prazosin in hypertension and heart failure; hypothesis-generating and should not yet change practice.
Structured PICO
P
Population
Patients with hypertension, congestive heart failure, or peripheral vasospasm (due to Raynaud's phenomenon or ergotamine overdose)
I
Intervention
Prazosin (orally active alpha-1 selective adrenergic antagonist)
Prazosin is a versatile alpha-1 adrenergic antagonist effective for managing hypertension and congestive heart failure with a favorable hemodynamic profile.
Cite This Study
Wilson S. Colucci (1982) conducted a review in Hypertension and congestive heart failure. Prazosin was evaluated. Prazosin is an effective alpha-1 selective adrenergic antagonist that provides sustained antihypertensive effects and hemodynamic improvement in congestive heart failure.