Key result
Calcium signalling silencing acts as an anti-arrhythmic adaptive response during short-term rapid atrial activation in atrial fibrillation, counteracting maladaptive intracellular changes.
Calcium signalling silencing is identified as a novel anti-arrhythmic adaptive mechanism in atrial fibrillation that counteracts intracellular calcium instability.
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May guide mechanism-based AF therapies; leaves open clinical translation pending prospective validation.
Maura Greiser (2017) conducted a review in Atrial fibrillation. Calcium signalling silencing was evaluated. Calcium signalling silencing acts as an anti-arrhythmic adaptive response during short-term rapid atrial activation in atrial fibrillation, counteracting maladaptive intracellular changes.
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