Why the study?
Are there temporal changes in frequency domain measures of heart rate variability before the onset of nonsustained versus sustained ventricular tachycardia in patients with coronary artery disease?
Population
n=18 patients with coronary artery disease at high risk of life-threatening arrhythmias.
Comparison
Analysis of frequency domain measures of heart… vs Comparison of HRV before nonsustained VT versus…
Design
Cohort
Key result
Frequency domain measures of heart rate variability, including total power, were significantly lower before the onset of sustained ventricular tachycardia than before nonsustained VT (p<0.001).
Authors
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Lower pre-onset HRV was associated with sustained VT in CAD; leaves open whether frequency-domain monitoring aids arrhythmia prediction.
Observational (n=18)
Are there temporal changes in frequency domain measures of heart rate variability before the onset of nonsustained versus sustained ventricular tachycardia in patients with coronary artery disease?
p-value: p=<0.001
Spontaneous episodes of sustained ventricular tachycardia are preceded by significantly lower heart rate variability compared to nonsustained episodes, suggesting divergent autonomic dynamics before arrhythmia onset.
Huikuri et al. (1993) conducted an observational in Coronary artery disease (n=18). Heart rate variability (HRV) frequency domain measures vs. Before nonsustained VT vs before sustained VT was evaluated on Frequency domain measures of HRV before the onset of nonsustained vs sustained VT (p=<0.001). Frequency domain measures of heart rate variability, including total power, were significantly lower before the onset of sustained ventricular tachycardia than before nonsustained VT (p<0.001).