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July 1, 1995The American Journal of CardiologyOpen Access

Impaired Low-Frequency Oscillations of Heart Rate in Patients With Prior Acute Myocardial Infarction and Life-Threatening Arrhythmias

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Why the study?

Does heart rate variability differ in patients with prior myocardial infarction and life-threatening arrhythmias compared to those without arrhythmic events?

Population

60 patients with a prior myocardial infarction, matched for age, sex, location, ejection fraction, number of…

Comparison

History of sustained ventricular tachycardia or… vs Prior myocardial infarction but no arrhythmic…

Design

Case-control

Authors

HHHeikki V. HuikuriElectrophysiologyMKM. Juhani KoistinenUniversity of TurkuSYSinikka Yli‐MäyryTampere University

Discussion

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Implication

May support HRV for post-MI VT risk stratification; leaves open whether it improves outcomes or warrants intervention.

Structured PICO

Does heart rate variability differ in patients with prior myocardial infarction and life-threatening arrhythmias compared to those without arrhythmic events?

P
Population
60 patients with a prior myocardial infarction, matched for age, sex, location, ejection fraction, number of prior infarctions, number of diseased coronary arteries, and beta-blocking medication.
I
Intervention
History of sustained ventricular tachycardia (n=18) or cardiac arrest (n=12)
C
Comparator
Prior myocardial infarction but no arrhythmic events (n=30)
O
Outcome
Heart rate variability in the time and frequency domain (SD of RR intervals and power spectral components)surrogate

Reduced very low-frequency power of heart rate variability is a strong independent predictor of ventricular tachycardia susceptibility in patients with prior myocardial infarction.

Cite This Study

Huikuri et al. (1995) studied this question.

synapsesocial.com/papers/6a6fec486ceb2bbd16dfc107https://doi.org/10.1016/s0002-9149(99)80801-7

Topics

Ventricular arrhythmias
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Frequency domain measures of heart rate variability before the onset of nonsustained and sustained ventricular tachycardia in patients with coronary artery disease.1993 · 258 citations
  2. 2Relation between heart rate variability and spontaneous and induced ventricular arrhythmias in patients with coronary artery disease1995 · 65 citations
  3. 3Decreased heart rate variability and its association with increased mortality after acute myocardial infarction1987 · 4,025 citations
  4. 4Heart rate variability in relation to prognosis after myocardial infarction: Selection of optimal processing techniques1989 · 390 citations
  5. 5Influence of age on the relation between heart rate variability, left ventricular ejection fraction, frequency of ventricular extrasystoles, and sudden death after myocardial infarction.1992 · 29 citations