Key result
The elastic shear modulus of 2 mg/ml F-actin is on the order of several hundred pascals, depending strongly on filament length and sample history, confirming F-actin networks can stabilize cells.
Population
Gels formed by purified actin filaments
Design
Preclinical
Authors
Loading...
Hypothesis-generating for cytoskeletal stability; leaves open validation in cardiovascular models.
Relatively isotropic F-actin networks are sufficiently strong to stabilize cells, with their elastic shear modulus depending strongly on filament length and sample history.
Janmey et al. (1994) studied this question. The elastic shear modulus of 2 mg/ml F-actin is on the order of several hundred pascals, depending strongly on filament length and sample history, confirming F-actin networks can stabilize cells.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: