Key result
Percutaneous coronary intervention significantly improved coronary hemodynamics, with the post-intervention change in iFR (0.20) being similar to the change in FFR (0.22; p=0.25).
Why the study?
Does percutaneous coronary intervention improve instantaneous wave-free ratio (iFR) similarly to fractional flow reserve (FFR) in patients with significant coronary stenosis?
Observational (n=112)
Yes
Does percutaneous coronary intervention improve instantaneous wave-free ratio (iFR) similarly to fractional flow reserve (FFR) in patients with significant coronary stenosis?
p-value: p=0.25
iFR can effectively detect improvements in coronary hemodynamics following PCI, demonstrating a dynamic range similar to FFR.
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iFR may gauge post-PCI hemodynamic response in cohorts; leaves open randomized confirmation of equivalence to FFR.
Nijjer et al. (2013) conducted an observational in Coronary stenoses (n=112). Percutaneous coronary intervention (PCI) vs. Pre-PCI baseline was evaluated on Change in instantaneous wave-free ratio (iFR) compared to fractional flow reserve (FFR) after PCI (p=0.25). Percutaneous coronary intervention significantly improved coronary hemodynamics, with the post-intervention change in iFR (0.20) being similar to the change in FFR (0.22; p=0.25).
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