Key result
Coronary flow reserve in response to intracoronary papaverine was significantly impaired in syndrome X patients compared to heart transplant controls (2.72 vs 5.22; P<0.01).
Why the study?
Does intracoronary papaverine reveal impaired coronary flow reserve in patients with syndrome X compared to controls?
Population
79 patients, comprising 53 with syndrome X and 26 heart transplant patients with normal coronary arteries.
Comparison
Intracoronary papaverine administered via 3.6F… vs Heart transplant patients with normal coronary…
Design
Case-control
Authors
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Should not change syndrome X evaluation; supports consensus on impaired reserve but challenges recent normal papaverine reports.
Case-Control (n=79)
Does intracoronary papaverine reveal impaired coronary flow reserve in patients with syndrome X compared to controls?
Absolute Event Rate: 2.72% vs 5.22%
p-value: p=<0.01
Coronary flow reserve in response to intracoronary papaverine is significantly impaired in patients with syndrome X compared to heart transplant controls.
Chauhan et al. (1994) conducted a case-control in Syndrome X (n=79). Intracoronary papaverine vs. Heart transplant patients (control group) was evaluated on Coronary flow reserve (p=<0.01). Coronary flow reserve in response to intracoronary papaverine was significantly impaired in syndrome X patients compared to heart transplant controls (2.72 vs 5.22; P<0.01).
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