Key result
Microalbumin measurement alone in spot urine was as reliable as the albumin/creatinine ratio (AUC 0.94 vs 0.94) for detecting microalbuminuria in hypertensive patients.
Why the study?
Does spot urine microalbumin measurement alone perform as well as the albumin/creatinine ratio (ACR) for the screening of microalbuminuria in hypertensive patients?
Cross-Sectional (n=264)
Does spot urine microalbumin measurement alone perform as well as the albumin/creatinine ratio (ACR) for the screening of microalbuminuria in hypertensive patients?
Absolute Event Rate: 0.94% vs 0.94%
Spot urine microalbumin measurement alone is as accurate as the albumin/creatinine ratio for screening microalbuminuria in hypertensive patients, offering a simpler approach without the need for creatinine determination or gender-specific cut-offs.
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May simplify microalbuminuria screening in hypertension; hypothesis-generating pending prospective validation.
Derhaschnig et al. (2002) conducted a cross-sectional in Hypertension (n=264). Microalbumin measurement alone in spot urine vs. Albumin/creatinine ratio (ACR) in spot urine was evaluated on Diagnostic performance (AUC) for detecting pathologic microalbuminuria (>30 mg/l in 24-h urine) (95% CI 0.90-0.98). Microalbumin measurement alone in spot urine was as reliable as the albumin/creatinine ratio (AUC 0.94 vs 0.94) for detecting microalbuminuria in hypertensive patients.
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