Key result
Urinary albumin/creatinine concentration ratio strongly correlated with urinary albumin excretion rate (r=0.81, P<0.001) and demonstrated 73% sensitivity and 97% specificity for detecting microalbuminuria.
Why the study?
Does measurement of urinary albumin/creatinine concentration ratio accurately detect microalbuminuria compared to urinary albumin excretion rate in a general population?
Cross-Sectional (n=2,579)
Does measurement of urinary albumin/creatinine concentration ratio accurately detect microalbuminuria compared to urinary albumin excretion rate in a general population?
Effect estimate: r = 0.81
p-value: p=<0.001
Measurement of the urinary albumin/creatinine concentration ratio is a specific and sensitive alternative to timed urine collections for microalbuminuria screening.
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Spot ACR offers a convenient screening option in general populations; leaves open need for prospective outcome validation against timed collections.
A 1997 study conducted a cross-sectional in Microalbuminuria (n=2,579). Urinary albumin/creatinine concentration ratio (Ualb/Ucreat) vs. Urinary albumin excretion rate (UAER) was evaluated on Correlation between Ualb/Ucreat and UAER (r = 0.81, p=<0.001). Urinary albumin/creatinine concentration ratio strongly correlated with urinary albumin excretion rate (r=0.81, P<0.001) and demonstrated 73% sensitivity and 97% specificity for detecting microalbuminuria.
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