Key result
Accelerated 4D phase-contrast MRI quantified net flow and regurgitant fractions across cardiac valves that were highly correlated with conventional planar MRI (correlation 0.917-0.972).
Why the study?
Does accelerated 4D-PC MRI accurately quantify net and regurgitant flow volume through cardiac valves compared to conventional cardiac MRI in pediatric patients with congenital heart disease?
Observational (n=34)
Does accelerated 4D-PC MRI accurately quantify net and regurgitant flow volume through cardiac valves compared to conventional cardiac MRI in pediatric patients with congenital heart disease?
Accelerated 4D-PC MRI provides consistent and reliable quantification of net and regurgitant blood flow across cardiac valves compared to conventional MRI in pediatric patients.
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May support faster valve flow quantification in congenital heart disease; leaves open prospective validation before clinical adoption.
Hsiao et al. (2014) conducted an observational in congenital, structural heart disease (n=34). Accelerated 4D phase-contrast magnetic resonance imaging (4D-PC MRI) vs. Conventional cardiac MRI was evaluated on Net and regurgitant flow volume through each of the cardiac valves. Accelerated 4D phase-contrast MRI quantified net flow and regurgitant fractions across cardiac valves that were highly correlated with conventional planar MRI (correlation 0.917-0.972).
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