Key result
Primary aldosteronism patients with type 2 diabetes mellitus required significantly more antihypertensive agents than those without diabetes to achieve comparable blood pressure control (2.0 vs. 1.3 agents, P=0.026).
Why the study?
Does the presence of type 2 diabetes mellitus increase the number of antihypertensive drugs required for blood pressure control in patients with primary aldosteronism?
Population
70 patients diagnosed with primary aldosteronism, including 18 with type 2 diabetes mellitus and 52 age- and…
Comparison
Primary aldosteronism with coexisting type 2… vs Primary aldosteronism without type 2 diabetes…
Design
Cohort
Authors
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PA patients with T2DM may need more antihypertensives for BP control; leaves open whether diabetes independently worsens PA-related hypertension.
Observational (n=70)
No
Does the presence of type 2 diabetes mellitus increase the number of antihypertensive drugs required for blood pressure control in patients with primary aldosteronism?
Absolute Event Rate: 2% vs 1.3%
p-value: p=0.026
Ohashi et al. (2018) conducted an observational in Primary Aldosteronism with Type 2 Diabetes Mellitus (n=70). Type 2 Diabetes Mellitus (comorbidity) vs. No Type 2 Diabetes Mellitus was evaluated on Number of antihypertensive drugs used (p=0.026). Primary aldosteronism patients with type 2 diabetes mellitus required significantly more antihypertensive agents than those without diabetes to achieve comparable blood pressure control (2.0 vs. 1.3 agents, P=0.026).
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