Key result
Primary aldosteronism was associated with a higher prevalence of chronic heart disease (29.3% vs 12.0%, p<0.05) and microalbuminuria (61.0% vs 41.6%, p<0.05) compared to essential hypertension.
Why the study?
Does primary aldosteronism increase the prevalence of cardiovascular complications compared to essential hypertension?
Population
248 patients aged 19-86 years with suspected primary aldosteronism, of which 41 had confirmed PA and the…
Comparison
Primary aldosteronism vs Essential hypertension
Design
Cross-sectional
Authors
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May warrant targeted PA screening in complicated hypertension; leaves open causal confirmation via prospective studies.
Observational (n=248)
Does primary aldosteronism increase the prevalence of cardiovascular complications compared to essential hypertension?
Absolute Event Rate: 29.3% vs 12%
p-value: p=<0.05
Primary aldosteronism is associated with a significantly higher prevalence of chronic heart disease and microalbuminuria compared to essential hypertension.
Khokhunov et al. (2017) conducted an observational in Primary hyperaldosteronism (n=248). Primary aldosteronism vs. Essential hypertension was evaluated on Chronic heart disease (p=<0.05). Primary aldosteronism was associated with a higher prevalence of chronic heart disease (29.3% vs 12.0%, p<0.05) and microalbuminuria (61.0% vs 41.6%, p<0.05) compared to essential hypertension.
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