Why the study?
Does reading of echocardiograms by cardiologists compared to sonographers improve reader agreement and reduce variability in left ventricular mass measurements in a multicenter trial?
Population
902 men and women with mild hypertension from four clinical centers participating in the Treatment of Mild…
Comparison
Echocardiographic measurement of left… vs Echocardiographic measurement of left…
Design
The underlying TOMHS trial was randomized, but this is a methodological…
Authors
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Cardiologist readings enhance LVM agreement in multicenter trials; extends evidence that reader expertise affects sample size and power.
Does reading of echocardiograms by cardiologists compared to sonographers improve reader agreement and reduce variability in left ventricular mass measurements in a multicenter trial?
Cardiologist readings of echocardiograms for left ventricular mass in multicenter trials yield higher agreement and lower variability compared to sonographer readings, which can appreciably affect sample size and power requirements.
Grandits et al. (1994) studied this question.
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