Key result
A literature review suggests that nearly 20% of the variability in depressive symptoms and coronary artery disease may be attributable to common genetic factors.
Design
Review
Authors
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No immediate change to depression or CAD management; leaves open genomic studies of shared vulnerability.
Shared genetic vulnerability, particularly in inflammation and serotonin pathways, may partially explain the covariation between depressive symptoms and coronary artery disease.
McCaffery et al. (2006) conducted a review in Depressive symptoms and Coronary Artery Disease. A literature review suggests that nearly 20% of the variability in depressive symptoms and coronary artery disease may be attributable to common genetic factors.
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