What question did this study set out to answer?

To present the 2015 updates, feature expansions, and technical improvements to the Simple Modular Architecture Research Tool (SMART) database.

October 9, 2014Nucleic Acids ResearchOpen Access

SMART: recent updates, new developments and status in 2015

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To present the 2015 updates, feature expansions, and technical improvements to the Simple Modular Architecture Research Tool (SMART) database.
Manually curated hidden Markov models for over 1,200 protein domains, integrating approximately 200 new domain models.
Synchronized underlying protein datasets with UniProt, Ensembl, and STRING databases.
Rebuilt the visual schematic architecture with a vector-based rendering engine and updated taxonomic tree navigation.
Expanded total annotated protein domains and functional features to more than 100 million entries across databases.
Increased Genomic mode coverage from 1,133 species to 2,031 completely sequenced species.
Implemented exportable vector-based schematics, updated result interfaces, and integrated search-enabled taxonomic tree displays.

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Implication

Database update demonstrates expanded protein domain annotations across sequenced genomes, highlighting improved bioinformatics tools for exploring protein architectures.

Cite This Study

Letunić et al. (2014) studied this question.

synapsesocial.com/papers/6a15e34f12229ed7d8d129ee https://doi.org/10.1093/nar/gku949

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Implication

Database update demonstrates expanded protein domain annotations across sequenced genomes, highlighting improved bioinformatics tools for exploring protein architectures.

SMART: recent updates, new developments and status in 2015

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Implication

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SMART: recent updates, new developments and status in 2015

Key Points

Discussion

Implication

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