Key result
Low-dose ATP sensitivity in slow-fast AVNRT was associated with a significantly higher prevalence of a lower common pathway compared to nonsensitive patients (88.2% vs 0%, P<0.0001).
Why the study?
The clinical implications and mechanism of low-dose adenosine triphosphate (LD-ATP) sensitivity in atrioventricular nodal reentrant tachycardia (AVNRT) remained unknown.
Does low-dose ATP sensitivity predict the presence of a lower common pathway and ablation site location in patients with slow-fast AVNRT?
Observational (n=28)
Does low-dose ATP sensitivity predict the presence of a lower common pathway and ablation site location in patients with slow-fast AVNRT?
Absolute Event Rate: 88.2% vs 0%
p-value: p=<0.0001
Low-dose ATP sensitivity in slow-fast AVNRT predicts the presence of a lower common pathway and indicates a successful ablation site closer to the His bundle.
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LD-ATP sensitivity may identify lower common pathway in slow-fast AVNRT; hypothesis-generating for His-proximal ablation site selection.
Watanabe et al. (2018) conducted an observational in slow-fast atrioventricular nodal reentrant tachycardia (n=28). Low-dose adenosine triphosphate (LD-ATP) vs. LD-ATP nonsensitive patients was evaluated on Prevalence of a lower common pathway (LCP) (p=<0.0001). Low-dose ATP sensitivity in slow-fast AVNRT was associated with a significantly higher prevalence of a lower common pathway compared to nonsensitive patients (88.2% vs 0%, P<0.0001).
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