Key result
Atherogenic index of plasma and mean platelet volume were significantly higher in heart failure patients compared with controls (p=0.002 and p=0.03) and independently predicted ejection fraction.
Why the study?
The study evaluated the relationship and diagnostic value of atherogenic index of plasma and mean platelet volume for heart failure and ejection fraction.
Are atherogenic index of plasma and mean platelet volume associated with ejection fraction and diagnostic of heart failure?
Case-Control (n=183)
Are atherogenic index of plasma and mean platelet volume associated with ejection fraction and diagnostic of heart failure?
Answers are grounded in this paper and cite their sources.
Atherogenic index of plasma and mean platelet volume are elevated in heart failure patients and independently predict ejection fraction, suggesting potential diagnostic utility.
AIM: Our aim was to evaluate the relationship and diagnostic value of atherogenic index of plasma (AIP) and mean platelet volume (MPV) for heart failure (HF) and ejection fraction (EF). MATERIALS AND METHODS: In the present study, AIP and MPV were studied in 114 stable HF patients (48 ischemic [42.1%], 66 nonischemic [57.9%]) and 69 controls. RESULTS: Mean AIP and MPV were significantly higher in HF compared with controls (p = 0.002; p = 0.03). In multivariate analysis, AIP and MPV were independently associated with EF. In receiver-operating characteristics (ROC) curve analysis both of them had optimal diagnostic value for HF. CONCLUSION: AIP and MPV regardless of ischemic etiology, were significantly higher in HF compared with controls. Both AIP and MPV are independent predictors of EF and have cut-off values for diagnosis of HF.
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Karadağ et al. (2018) conducted a case-control in Heart failure (n=183). Atherogenic index of plasma (AIP) and mean platelet volume (MPV) vs. Controls was evaluated on Heart failure diagnosis and ejection fraction (p=0.002; 0.03). Atherogenic index of plasma and mean platelet volume were significantly higher in heart failure patients compared with controls (p=0.002 and p=0.03) and independently predicted ejection fraction.
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