Key result
Stentless valve replacement yielded significantly greater early improvement in left ventricular fractional shortening (25.6% vs 17.0%; P<0.001) compared with stented valves.
Why the study?
Does stentless aortic valve replacement improve early left ventricular systolic function compared to stented valve replacement in patients with significant aortic stenosis and impaired LV function?
Population
33 patients with significant aortic stenosis and impaired left ventricular systolic function, without…
Comparison
Stentless aortic valve replacement vs Stented aortic valve replacement (n=13)
Design
Cohort
Follow-up
before discharge from the hospital
Authors
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May support stentless valves for faster early LV recovery in impaired function; hypothesis-generating and requires RCT confirmation.
Cohort (n=33)
Does stentless aortic valve replacement improve early left ventricular systolic function compared to stented valve replacement in patients with significant aortic stenosis and impaired LV function?
Absolute Event Rate: 25.6% vs 17%
p-value: p=<0.001
Stentless aortic valve replacement provides significantly greater early improvement in left ventricular systolic function compared to stented valves in patients with aortic stenosis and impaired LV function.
Collinson et al. (1999) conducted a cohort in Aortic stenosis with impaired LV systolic function (n=33). Stentless valve vs. Stented valve was evaluated on Postoperative fractional shortening (p=<0.001). Stentless valve replacement yielded significantly greater early improvement in left ventricular fractional shortening (25.6% vs 17.0%; P<0.001) compared with stented valves.
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