Key result
Ultrasmall superparamagnetic iron oxide particles, particularly ferumoxtran-10 and ferumoxytol, show potential for assessing atheromatous plaque inflammation in atherosclerosis imaging.
Design
Review
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May support noninvasive plaque inflammation assessment; leaves open prospective validation before clinical use.
Ultrasmall superparamagnetic iron oxide particles offer a promising MRI contrast method for visualizing inflammation within atherosclerotic plaques, overcoming limitations of conventional imaging.
Usman et al. (2015) conducted a review in Carotid Atherosclerosis. Ultrasmall superparamagnetic iron oxide particles (ferumoxtran-10 and ferumoxytol) was evaluated. Ultrasmall superparamagnetic iron oxide particles, particularly ferumoxtran-10 and ferumoxytol, show potential for assessing atheromatous plaque inflammation in atherosclerosis imaging.
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