Key result
Selecting cryoablation patients using contrast-enhanced CT is linked to ~92% sinus rhythm maintenance.
Why the study?
Cryoballoon PVI durability may be reduced by anatomical factors, PV position, and inadequate carina isolation leading to AF recurrence.
Does patient selection using contrast-enhanced CT improve early success rates and prevent AF recurrence in paroxysmal AF patients undergoing PVI with cryoballoon?
Observational (n=50)
No
Does patient selection using contrast-enhanced CT improve early success rates and prevent AF recurrence in paroxysmal AF patients undergoing PVI with cryoballoon?
Answers are grounded in this paper and cite their sources.
Selecting patients for cryoballoon ablation based on contrast-enhanced CT to ensure optimal pulmonary vein anatomy yields high single-freeze isolation success (96%) and excellent 1-year sinus rhythm maintenance (92%).
PURPOSE: Compared with conventional pulmonary vein isolation (PVI) with radiofrequency ablation, PVI with cryoballoon is an easier and shorter procedure without reconnection, particularly in the superior pulmonary vein. However, the durability of the cryoballoon may be reduced due to anatomical factors and the position of the pulmonary vein (PV). Further, inadequate isolation of the carina leads to recurrence of atrial fibrillation (AF). We aimed to determine whether using contrast-enhanced computed tomography (CT) for patient selection improves the early success rate and prevents the recurrence of AF in PVI with cryoballoon. METHODS: We evaluated patients who underwent ablation for paroxysmal atrial fibrillation in our hospital between July 2019 and November 2020. After excluding patients with contraindications for cryoablation, 50 patients were selected through visual inspection of the results of preoperative contrast-enhanced CT. A treatment plan was established, and the clinical course and outcomes were followed up. RESULTS: Of the 200 PVs of the 50 patients, only 8 PVs (4%) were incompletely isolated with a single cryoablation. Six of the eight PVs were successfully isolated with additional cryoablation. Only 2 patients (4%) underwent additional PVI with radiofrequency ablation. Four patients had AF recurrence within a mean follow-up period of 14.3 ± 5.1 months. The rate of sinus rhythm maintenance was 92%. PV reconnection was observed in 2 patients. None of the patients had postoperative atrial flutter. CONCLUSIONS: Selecting patients for cryoablation according to contrast-enhanced CT findings made the procedure easier to perform, leading to improved early success rates and clinical course.
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Sakamoto et al. (2021) conducted an observational in paroxysmal atrial fibrillation (n=50). Contrast-enhanced CT-guided pulmonary vein isolation with cryoablation was evaluated on Sinus rhythm maintenance. Selecting patients for cryoablation according to contrast-enhanced CT findings resulted in a 92% rate of sinus rhythm maintenance over a mean follow-up of 14.3 months.
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